A final rule placing the opioid analgesic tramadol in Schedule IV was published on July 2 with an effective date of Aug. 18 (79 Fed. Reg. 37622). Tramadol drug products are approved in the United States for treatment of moderate to moderately severe pain. Tramadol drugs have been marketed for several years in Europe and Canada. The first U.S. approval was in 1995 for Ultram™ (Jans... Read More